RAD51 Antikörper (AA 1-339)
Kurzübersicht für RAD51 Antikörper (AA 1-339) (ABIN6242792)
Target
Alle RAD51 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Bindungsspezifität
- AA 1-339
-
Aufreinigung
- This antibody is purified through a protein G column, followed by dialysis against PBS.
-
Immunogen
- This RAD51 antibody is generated from a mouse immunized with a recombinant protein between 1-339 amino acids from human RAD51.
-
Isotyp
- IgG2b kappa
-
-
-
-
Applikationshinweise
- WB: 1:4000
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Haltbarkeit
- 6 months
-
-
- RAD51 (DNA Repair Protein Homolog 1 (RAD51))
-
Andere Bezeichnung
- RAD51
-
Hintergrund
- Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.
-
Molekulargewicht
- 36966
-
UniProt
- Q06609
-
Pathways
- DNA Reparatur
Target
-