MLH1 Antikörper (C-Term)
Kurzübersicht für MLH1 Antikörper (C-Term) (ABIN6242443)
Target
Alle MLH1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- C-Term
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Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-term region of human MLH1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- WB: 1:1000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- MLH1 (MutL Homolog 1 (MLH1))
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Andere Bezeichnung
- MLH1
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Hintergrund
- MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). The protein is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.
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Molekulargewicht
- 84601
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NCBI Accession
- NP_000240, NP_001161089, NP_001161090, NP_001161091, NP_001245200, NP_001245202, NP_001245203
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UniProt
- P40692
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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