MLH1
Reaktivität: Human
ELISA, IHC (p), IF (p), IF (cc), IHC (fro)
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Target
MLH1
(MutL Homolog 1 (MLH1))
Andere Bezeichnung
MLH1
Hintergrund
MLH1 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). The protein is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC.