PTEN Antikörper (pSer385)
Kurzübersicht für PTEN Antikörper (pSer385) (ABIN6241050)
Target
Alle PTEN Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer385
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Homologie
- M, X
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This PTEN Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S385 of human PTEN.
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Isotyp
- Ig Fraction
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anti-Phosphatase and Tensin Homolog (PTEN) (AA 69-104), (N-Term) antibody
PTEN Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB05082 unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 69-104) antibodyPTEN Reaktivität: Human WB, ELISA, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 264-295), (C-Term) antibodyPTEN Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB5083 unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 264-295) antibodyPTEN Reaktivität: Human WB, ELISA, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 306-335) antibodyPTEN Reaktivität: Human WB, ELISA, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 363-392) antibodyPTEN Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB39439 unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (C-Term) antibodyPTEN Reaktivität: Human, Maus, Ratte, Schwein, Affe, Hund WB, IF, IHC, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (C-Term), (pSer380), (pThr382), (pThr383) antibodyPTEN Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund WB, IF, IHC, IP, IC Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 371-403) antibodyPTEN Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Phosphatase and Tensin Homolog (PTEN) (AA 10-44), (N-Term) antibodyPTEN Reaktivität: Human, Maus, Ratte WB Wirt: Maus Monoclonal 1096CT4-3-3 unconjugated
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Applikationshinweise
- DB: 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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- PTEN (Phosphatase and Tensin Homolog (PTEN))
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Andere Bezeichnung
- PTEN
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Hintergrund
- This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.
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Molekulargewicht
- 47166
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NCBI Accession
- NP_000305
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UniProt
- P60484
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Inositol Metabolic Process, Synaptic Membrane, Regulation of Cell Size, Autophagie, Platelet-derived growth Factor Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Target
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