Fibrillarin Antikörper
Kurzübersicht für Fibrillarin Antikörper (ABIN3021515)
Target
Alle Fibrillarin (FBL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein of human FBL
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C/-80 °C
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: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).
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: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).
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- Fibrillarin (FBL)
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Andere Bezeichnung
- FBL
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Hintergrund
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Fibrillarin is a 2-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.
Synonyms: FBL, FIB, FLRN, RNU3IP1 -
Gen-ID
- 2091
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UniProt
- P22087
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Pathways
- Ribonucleoside Biosynthetic Process
Target
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