FSHR Antikörper (CF®405S)
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- Target Alle FSHR Antikörper anzeigen
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FSHR Antikörper ist konjugiert mit CF®405S
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Applikation
- Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Verwendungszweck
- Mouse Monoclonal anti-FSH Receptor (FSHR/1400), CF405S Conjugate
- Produktmerkmale
- Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its ? and ? subunits. While the ? subunit of FSH is involved in the binding of FSH to the receptor, the ? subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- Immunogen
- Recombinant human full-length FSHR protein
- Klon
- FSHR-1400
- Isotyp
- IgG1
- Top Product
- Discover our top product FSHR Primärantikörper
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- Applikationshinweise
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Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA
- pH 9.0
- or 10 mM citrate buffer
- pH 6.0
- for 10-20 min followed by cooling at RT for 20 min
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
- Kommentare
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Uterine Carcinoma
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 100 μg/mL
- Buffer
- PBS/0.1 % BSA/0.05 % azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Protect from light
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- Target
- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
- Andere Bezeichnung
- FSH Receptor (FSHR Produkte)
- Synonyme
- FSHRO antikoerper, LGR1 antikoerper, ODG1 antikoerper, FSH-R antikoerper, eFSHR antikoerper, FSHRE antikoerper, fshr antikoerper, FSHR antikoerper, fshr-A antikoerper, GTHR-I antikoerper, zfGTHR-I antikoerper, LOC100304505 antikoerper, follicle stimulating hormone receptor antikoerper, follicle stimulating hormone receptor L homeolog antikoerper, follicle-stimulating hormone receptor antikoerper, FSHR antikoerper, fshr antikoerper, Fshr antikoerper, fshr.L antikoerper, Bm1_17785 antikoerper, LOC100304505 antikoerper
- Hintergrund
- Follicle-stimulating hormone receptor, Follitropin receptor, FSH receptor, FSH-R, FSHRO, LGR1, ODG1, ovarian dysgenesis 1
- Molekulargewicht
- 75 kDa
- Gen-ID
- 2492, 1428
- UniProt
- P23945
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
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