CD46 Antikörper (APC)
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- Target Alle CD46 Antikörper anzeigen
- CD46
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Reaktivität
- Human, Rind (Kuh)
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD46 Antikörper ist konjugiert mit APC
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- This antibody recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein). CD46 is 56-66 kDa dimeric transmembrane protein expressed on T and B lymphocytes, platelets, monocytes, granulocytes, endothelial cells, epithelial cells and fibroblast, it is negative on erythrocytes.
- Kreuzreaktivität (Details)
- Species reactivity (tested):Human, bovine
- Immunogen
- HPB-ALL human T cell line
- Klon
- MEM-258
- Isotyp
- IgG1
- Top Product
- Discover our top product CD46 Primärantikörper
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anti-CD46 (CD46) (AA 35-179) antibody
CD46 Reaktivität: Human FACS, ELISA, IHC Wirt: Maus Monoclonal 1A5A5 unconjugated
anti-CD46 (CD46) (AA 35-179) antibodyCD46 Reaktivität: Human WB, FACS, ELISA, ICC Wirt: Maus Monoclonal 5A8C11 unconjugated
anti-CD46 (CD46) (AA 40-320) antibodyCD46 Reaktivität: Human WB, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343) antibodyCD46 Reaktivität: Human WB, FACS, IF, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) antibodyCD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 unconjugated
anti-CD46 (CD46) (AA 251-355) antibodyCD46 Reaktivität: Human, Maus WB, FACS, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-CD46 (CD46) (AA 317-343), (C-Term) antibodyCD46 Reaktivität: Human WB, FACS, IF, IHC (p) Wirt: Kaninchen Polyclonal RB21743 unconjugated
anti-CD46 (CD46) antibody (Biotin)CD46 Reaktivität: Human, Rind (Kuh) WB, FACS, IP Wirt: Maus Monoclonal MEM-258 Biotin
anti-CD46 (CD46) antibody (FITC)CD46 Reaktivität: Human, Rind (Kuh) FACS Wirt: Maus Monoclonal MEM-258 FITC
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Dilute only prior to immediate use
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
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- Target
- CD46
- Andere Bezeichnung
- CD46 / MCP (CD46 Produkte)
- Hintergrund
- CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
- Gen-ID
- 4179
- NCBI Accession
- NP_002380
- UniProt
- P15529
- Pathways
- Regulation of Actin Filament Polymerization
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