SMO Antikörper (N-Term)
Kurzübersicht für SMO Antikörper (N-Term) (ABIN615867)
Target
Alle SMO Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- This antibody reacts to the N-term of Smoothened Homolog (SMOH).
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Aufreinigung
- Immunoaffinity Chromatography
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Immunogen
- SMO antibody was raised against synthetic peptide - KLH conjugated Genename: SMO
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1,0 mg/mL
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Buffer
- PBS (without Mg2+, Ca2+), pH 7.4 containing 150 mM sodium chloride, 0.02 % sodium azide as preservative and 50 % glycerol as stabilizer
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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- SMO (Smoothened Homolog (Drosophila) (SMO))
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Andere Bezeichnung
- SMO
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Hintergrund
- Smoothened, a Frizzled Receptor, is homologous to the Drosophila segment polarity Smo gene. It associates with the Patched protein to mediate the cellular response to the Hedgehog secreted protein signal, which controls patterning and growth during vertebrate development. Smoothened is activated in a number of human tumors and can function as an oncogene in basal-cell carcinomas.Synonyms: Gx protein, SMOH, Smoothened homolog
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Gen-ID
- 6608
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NCBI Accession
- NP_005622
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UniProt
- Q99835
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Pathways
- Hedgehog Signalweg
Target
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