TLR7 Antikörper (AA 900-950)

Produktnummer ABIN615823

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TLR7 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Affe, Hund, Rind (Kuh) und Pferd.

Kurzübersicht für TLR7 Antikörper (AA 900-950) (ABIN615823)

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Reaktivität: Human, Maus, Ratte, Affe, Hund, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TLR7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TLR7 Antikörper

Bindungsspezifität: AA 900-950

Spezifität: This antibody reacts to Toll-like Receptor 7 (TLR7).

Aufreinigung: Protein G Chromatography

Immunogen: Synthetic peptide - KLH conjugated, A portion of amino acids 900-950 of human TLR7 Genename: TLR7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0,5 mg/mL

Buffer: PBS containing 0.2 % gelatin and 0.05 % sodium azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TLR7

Target: TLR7 (Toll-Like Receptor 7 (TLR7))

Andere Bezeichnung: TLR7

Hintergrund: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR7, like TLRs 3, 8, and 9, is localized in intracellular acidic compartments such as the phagolysosome and will recognize some single-stranded RNA viruses such as vesicular stomatitis virus (VSV) and influenza virus. Activation of TLR7 by VSV results in stimulation of the immune response including IFNa secretion, suggesting the importance of TLR7 in virus recognition.Synonyms: Toll-like receptor 7

Gen-ID: 51284

NCBI Accession: NP_057646

UniProt: Q9NYK1

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades