ITGAL Antikörper (CF®543)
Kurzübersicht für ITGAL Antikörper (CF®543) (ABIN6157791)
Target
Alle ITGAL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Mouse Monoclonal anti-CD11a (Cris-3), CF543 Conjugate
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Produktmerkmale
- This antibody recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop II, Code N202). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
- Stimulated human leukocytes
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Isotyp
- IgG2b kappa
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Applikationshinweise
- Immunofluorescence 0.5-1 μg/mLFlow Cytometry 0.5-1 μg/million cells/0.1 mL
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Kommentare
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JY, HUT-78, MOLT-4, HL60, U937, and human leukocytes. Human lymph nodes and tonsils.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100 μg/mL
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Buffer
- PBS/0.1 % BSA/0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Protect from light
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- ITGAL (Integrin alpha-L (ITGAL))
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Andere Bezeichnung
- CD11a
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Hintergrund
- Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide, Integrin alpha-L, ITGAL, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, LFA 1 alpha (LFA1A), Ly15, Ly21, p180
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Molekulargewicht
- 180 kDa
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Gen-ID
- 3683, 174103
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UniProt
- P20701
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Pathways
- Activated T Cell Proliferation, Integrin Complex
Target
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