Integrin Alpha2b Antikörper (CF®647)
Kurzübersicht für Integrin Alpha2b Antikörper (CF®647) (ABIN6156501)
Target
Alle Integrin Alpha2b (CD41) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
 - Mouse Monoclonal anti-CD41a (ITGA2B/1036), CF647 Conjugate
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Produktmerkmale
 - This antibody recognizes a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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Immunogen
 - Recombinant full-length human Integrin alpha IIb protein
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Isotyp
 - IgG1 kappa
 
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Applikationshinweise
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                        Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
 - Optimal dilution for a specific application should be determined by user
 
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Kommentare
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KG1a, HEL cells, and human platelets in lymph nodes or tonsils.
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 100 μg/mL
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Buffer
 - PBS/0.1 % BSA/0.05 % azide
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
 - Protect from light
 
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- Integrin Alpha2b (CD41)
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Andere Bezeichnung
 - CD41a
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Hintergrund
 - BDPLT16, BDPLT2, GPalpha IIb, GT, HPA3, Integrin alpha IIb, ITGA2B, ITGAB, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex
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Molekulargewicht
 - 90 kDa
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Gen-ID
 - 3674, 411312
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UniProt
 - P08514
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Pathways
 - Integrin Complex
 
Target
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