AMPD3 Antikörper (Biotin)

Produktnummer ABIN6155534

Dieses Anti-AMPD3-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von AMPD3 in IF, ICC, FACS und IHC (f). Geeignet für Human.

Kurzübersicht für AMPD3 Antikörper (Biotin) (ABIN6155534)

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AMPD3 Antikörper ist konjugiert mit Biotin

Applikation: Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon: AMPD3-901

Produktdetails anti-AMPD3 Antikörper (Biotin)

Verwendungszweck: Mouse Monoclonal anti-Adenosine Monophosphate Deaminase-3 (AMPD3) (AMPD3/901), Biotin Conjugate

Produktmerkmale: This antibody recognizes a protein of ~90 kDa, which is identified as Adenosine Monophosphate Deaminase, isoform E (AMPD3). It has 767 amino acids and is assigned an EC 3.5.4.6. It is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. AMPD3 gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. This MAb shows reactivity with cells of the erythroid lineage at all stages of maturation in the peripheral blood, bone marrow, and fetal liver. Non-erythroid lineages are negative by flow cytometry. This MAb is useful in the diagnosis of erythroleukemia, identification of bone marrow erythroid precursors, gating erythroid nucleated precursor cells from malignant cells in bone marrow specimens. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogen: Recombinant full-length human AMDP3 protein

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Immunohistology formalin-fixed 2-4 μg/mL

• Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
• Immunocytochemistry 1-2.0 μg/mL
• Immunofluorescence 0.5-1 μg/mL
• Flow Cytometry 1-2 μg/million cells in 0.1 mL
• Optimal dilution for a specific application should be determined by user

Kommentare:

RBC. Fetal liver, Spleen or Placenta

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS/0.1 % BSA/0.05 % azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Details zu AMPD3

Target: AMPD3 (Adenosine Monophosphate Deaminase 3 (AMPD3))

Andere Bezeichnung: Adenosine Monophosphate Deaminase-3 (AMPD3)

Molekulargewicht: 90 kDa

Gen-ID: 272, 501890

UniProt: Q01432