FGFR1 Antikörper (C-Term)

Produktnummer ABIN614919

Der Ziege Polyklonal anti-FGFR1 Antikörper (ABIN614919) detektiert spezifisch FGFR1 in WB, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Rind (Kuh) und Hund.

Kurzübersicht für FGFR1 Antikörper (C-Term) (ABIN614919)

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Reaktivität: Human, Rind (Kuh), Hund

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser FGFR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-FGFR1 Antikörper

Bindungsspezifität: C-Term

Sequenz: CLPRHPAQLA NGGLKR

Spezifität: This antibody detects CD331 / FGFR1 (C-term).

Kreuzreaktivität (Details): Species reactivity (expected):Cow, DogSpecies reactivity (tested):Human

Aufreinigung: Immunoaffinity chromatography

Immunogen: Synthetic peptide from C-term of human FGFR1 Genename: FGFR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline buffer, pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu FGFR1

Target: FGFR1 (Fibroblast Growth Factor Receptor 1 (FGFR1))

Andere Bezeichnung: FGFR1

Hintergrund: The fibroblast growth factor receptor 1 belongs to the FGF Receptor subfamily. The full-length protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. Ligand binding results in the activation of a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. Various isoforms of FGFR1 have been identified that differ in structure and specificity. Defects in FGFR1 cause craniofacial abnormalities in diseases such as Pfeiffer syndrome and Jackson-Weiss syndrome.Synonyms: BFGFR, Basic fibroblast growth factor receptor 1, CEK, FGFBR, FLG, FLT-2, FLT2, Fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, HBGFR, N-sam, Proto-oncogene c-Fgr, bFGF-R-1

Gen-ID: 2260

NCBI Accession: NP_056934

UniProt: P11362

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, S100 Proteine