SPHK2 Antikörper (AA 1-165)

Produktnummer ABIN6148347

Produktdetails anti-SPHK2 Antikörper

Target: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Bindungsspezifität: AA 1-165

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPHK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MNGHLEAEEQ QDQRPDQELT GSWGHGPRST LVRAKAMAPP PPPLAASTPL LHGEFGSYPA RGPRFALTLT SQALHIQRLR PKPEARPRGG LVPLAEVSGC CTLRSRSPSD SAAYFCIYTY PRGRRGARRR ATRTFRADGA ATYEENRAEA QRWATALTCL LRGLP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-165 of human SPHK2 (NP_001191088.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SPHK2

Target: SPHK2 (Sphingosine Kinase 2 (SPHK2))

Andere Bezeichnung: SPHK2 (SPHK2 Produkte)

Synonyme: CG2159 antikoerper, CG32484 antikoerper, Dmel\\CG32484 antikoerper, SK2 antikoerper, Sphk2 antikoerper, sk2 antikoerper, DKFZp469F224 antikoerper, SK 2 antikoerper, SK-2 antikoerper, SPK 2 antikoerper, SPK-2 antikoerper, C76851 antikoerper, Sphingosine kinase antikoerper, sphk2 antikoerper, Sphingosine kinase 2 antikoerper, sphingosine kinase 2 antikoerper, sphK2 antikoerper, Sk2 antikoerper, SPHK2 antikoerper, Sphk2 antikoerper

Hintergrund: This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.,SPHK2,SK 2,SK-2,SPK 2,SPK-2,SK2,SPK2,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Kinase,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,SPHK2

Molekulargewicht: 62 kDa/65 kDa/69 kDa/80 kDa

Gen-ID: 56848

UniProt: Q9NRA0

Pathways: VEGF Signaling