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Rubicon Antikörper (AA 1-200)

KIAA0226 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6147300
  • Target Alle Rubicon (KIAA0226) Antikörper anzeigen
    Rubicon (KIAA0226) (KIAA0226)
    Bindungsspezifität
    • 18
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-200
    Reaktivität
    • 33
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 31
    • 2
    Kaninchen
    Klonalität
    • 31
    • 2
    Polyklonal
    Konjugat
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser Rubicon Antikörper ist unkonjugiert
    Applikation
    • 29
    • 19
    • 14
    • 14
    • 10
    • 9
    • 5
    • 3
    Western Blotting (WB)
    Sequenz
    MRPEGAGMEL GGGEERLPEE SRREHWQLLG NLKTTVEGLV STNSPNVWSK YGGLERLCRD MQSILYHGLI RDQACRRQTD YWQFVKDIRW LSPHSALHVE KFISVHENDQ SSADGASERA VAELWLQHSL QYHCLSAQLR PLLGDRQYIR KFYTDAAFLL SDAHVTAMLQ CLEAVEQNNP RLLAQIDASM FARKHESPLL
    Kreuzreaktivität
    Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Rubicon (NP_055502.1).
    Isotyp
    IgG
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  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Rubicon (KIAA0226) (KIAA0226)
    Andere Bezeichnung
    RUBCN (KIAA0226 Produkte)
    Synonyme
    RUBICON antikoerper, 5330403K09 antikoerper, Kiaa0226 antikoerper, Rubicon antikoerper, mKIAA0226 antikoerper, RUN and cysteine rich domain containing beclin 1 interacting protein antikoerper, KIAA0226 antikoerper, RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein antikoerper, RUBCN antikoerper, KIAA0226 antikoerper, Rubcn antikoerper
    Hintergrund
    The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.,RUBCN,KIAA0226,RUBICON,SCAR15,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Cardiovascular,Heart,RUBCN
    Molekulargewicht
    102 kDa/103 kDa/108 kDa
    Gen-ID
    9711
    UniProt
    Q92622
    Pathways
    Autophagie
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