ROR2 Antikörper (AA 100-200)

Produktnummer ABIN6147075

Der Kaninchen Polyklonal Anti-ROR2-Antikörper wurde für WB und IHC validiert. Er ist geeignet, ROR2 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für ROR2 Antikörper (AA 100-200) (ABIN6147075)

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ROR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-ROR2 Antikörper

Bindungsspezifität: AA 100-200

Sequenz: APVVQEPRRI IIRKTEYGSR LRIQDLDTTD TGYYQCVATN GMKTITATGV LFVRLGPTHS PNHNFQDDYH EDGFCQPYRG IACARFIGNR TIYVDSLQMQ G

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human ROR2 (NP_004551.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-ROR2 Antikörper (ABIN6147075)

Fu, Wang, Wan, Lin, Chang, Han: "Wnt5a mediated canonical Wnt signaling pathway activation in orthodontic tooth movement: possible role in the tension force-induced bone formation." in: Journal of molecular histology, Vol. 47, Issue 5, pp. 455-66, (2017) (PubMed).

Details zu ROR2

Target: ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))

Andere Bezeichnung: ROR2

Hintergrund: The protein encoded by this gene is a receptor protein tyrosine kinase and type I transmembrane protein that belongs to the ROR subfamily of cell surface receptors. The protein may be involved in the early formation of the chondrocytes and may be required for cartilage and growth plate development. Mutations in this gene can cause brachydactyly type B, a skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In addition, mutations in this gene can cause the autosomal recessive form of Robinow syndrome, which is characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly, and a dysmorphic facial appearance.,ROR2,BDB,BDB1,NTRKR2,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Bone,Stem Cells,Mesenchymal Stem Cells,ROR2

Molekulargewicht: 104 kDa

Gen-ID: 4920

UniProt: Q01974

Pathways: RTK Signalweg, WNT Signalweg