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RAD51 Antikörper (AA 50-150)

Der Kaninchen Polyklonal Anti-RAD51-Antikörper wurde für WB validiert. Er ist geeignet, RAD51 in Proben von Human zu detektieren. Es sind 3+ Publikationen verfügbar.
Produktnummer ABIN6146636

Kurzübersicht für RAD51 Antikörper (AA 50-150) (ABIN6146636)

Target

Alle RAD51 Antikörper anzeigen
RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Reaktivität

  • 125
  • 76
  • 38
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 106
  • 22
  • 1
Kaninchen

Klonalität

  • 97
  • 32
Polyklonal

Konjugat

  • 74
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser RAD51 Antikörper ist unkonjugiert

Applikation

  • 96
  • 40
  • 29
  • 29
  • 28
  • 22
  • 21
  • 21
  • 11
  • 11
  • 9
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 23
    • 15
    • 11
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-150

    Sequenz

    EAVAYAPKKE LINIKGISEA KADKILAEAA KLVPMGFTTA TEFHQRRSEI IQITTGSKEL DKLLQGGIET GSITEMFGEF RTGKTQICHT LAVTCQLPID R

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Rad51 (NP_002866.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:1000

    Kommentare

    HIGH QUALITY

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Wang, Sun, Zhu, Sun, Ma, Wang, Lu, Chen, Xu: "Quantitative proteomic analysis revealed changes in protein synthesis and mitochondrial functions after acute DNA damage in mouse neural stem cells." in: Neuroscience letters, Vol. 653, pp. 355-361, (2018) (PubMed).

    Li, Zhang, Chen, Guo, Zhang, Tang, Xu, Zhang, Tao, Wang, Jiang, Sun, Mao: "Impaired DNA double-strand break repair contributes to the age-associated rise of genomic instability in humans." in: Cell death and differentiation, Vol. 23, Issue 11, pp. 1765-1777, (2017) (PubMed).

    Zhang, Tang, Jiang, Mao: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).

  • Target

    RAD51 (DNA Repair Protein Homolog 1 (RAD51))

    Andere Bezeichnung

    RAD51

    Hintergrund

    The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene.,RAD51,BRCC5,FANCR,HRAD51,HsRad51,HsT16930,MRMV2,RAD51A,RECA,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,RAD51

    Molekulargewicht

    26 kDa/31 kDa/36 kDa

    Gen-ID

    5888

    UniProt

    Q06609

    Pathways

    DNA Reparatur
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