Poliovirus Receptor Antikörper (AA 220-345)
Kurzübersicht für Poliovirus Receptor Antikörper (AA 220-345) (ABIN6146508)
Target
Alle Poliovirus Receptor (PVR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 220-345
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Sequenz
- TCKVEHESFE KPQLLTVNLT VYYPPEVSIS GYDNNWYLGQ NEATLTCDAR SNPEPTGYNW STTMGPLPPF AVAQGAQLLI RPVDKPINTT LICNVTNALG ARQAELTVQV KEGPPSEHSG MSRNAI
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 220-345 of human CD155/PVR (NP_006496.4).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Poliovirus Receptor (PVR)
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Andere Bezeichnung
- PVR
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Hintergrund
- The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.,PVR,CD155,HVED,NECL5,Necl-5,PVS,TAGE4,Immunology & Inflammation,CD markers,PVR
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Molekulargewicht
- 39 kDa/40 kDa/42 kDa/45 kDa
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Gen-ID
- 5817
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UniProt
- P15151
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom
Target
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