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PLAT Antikörper (AA 23-320)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PLAT in WB. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6145743

Kurzübersicht für PLAT Antikörper (AA 23-320) (ABIN6145743)

Target

Alle PLAT Antikörper anzeigen
PLAT (Plasminogen Activator, Tissue (PLAT))

Reaktivität

  • 98
  • 70
  • 50
  • 8
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 109
  • 29
  • 20
  • 2
  • 1
Kaninchen

Klonalität

  • 119
  • 41
Polyklonal

Konjugat

  • 86
  • 15
  • 11
  • 8
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser PLAT Antikörper ist unkonjugiert

Applikation

  • 126
  • 64
  • 57
  • 41
  • 40
  • 26
  • 26
  • 11
  • 10
  • 9
  • 5
  • 5
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 15
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-320

    Sequenz

    SQEIHARFRR GARSYQVICR DEKTQMIYQQ HQSWLRPVLR SNRVEYCWCN SGRAQCHSVP VKSCSEPRCF NGGTCQQALY FSDFVCQCPE GFAGKCCEID TRATCYEDQG ISYRGTWSTA ESGAECTNWN SSALAQKPYS GRRPDAIRLG LGNHNYCRNP DRDSKPWCYV FKAGKYSSEF CSTPACSEGN SDCYFGNGSA YRGTHSLTES GASCLPWNSM ILIGKVYTAQ NPSAQALGLG KHNYCRNPDG DAKPWCHVLK NRRLTWEYCD VPSCSTCGLR QYSQPQFRIK GGLFADIA

    Kreuzreaktivität

    Human

    Produktmerkmale

    Polyclonal Antibodies

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 23-320 of human tPA/tPA/PLAT (NP_000921.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Kommentare

    HIGH QUALITY

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    PLAT (Plasminogen Activator, Tissue (PLAT))

    Andere Bezeichnung

    PLAT

    Hintergrund

    This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.,PLAT,T-PA,TPA,Cancer,Cell Biology & Developmental Biology,Ubiquitin,Endocrine & Metabolism,Cardiovascular,Blood,Serum Proteins,Hypoxia,PLAT

    Molekulargewicht

    32 kDa/44 kDa/57 kDa/62 kDa

    Gen-ID

    5327

    UniProt

    P00750

    Pathways

    Autophagie, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interaktom
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