NADPH Oxidase 4 Antikörper (AA 328-578)

Produktnummer ABIN6144752

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch NADPH Oxidase 4 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für NADPH Oxidase 4 Antikörper (AA 328-578) (ABIN6144752)

Target: NADPH Oxidase 4 (NOX4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NADPH Oxidase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-NADPH Oxidase 4 Antikörper

Bindungsspezifität: AA 328-578

Sequenz: KENFKARPGQ YITLHCPSVS ALENHPFTLT MCPTETKATF GVHLKIVGDW TERFRDLLLP PSSQDSEILP FIQSRNYPKL YIDGPFGSPF EESLNYEVSL CVAGGIGVTP FASILNTLLD DWKPYKLRRL YFIWVCRDIQ SFRWFADLLC MLHNKFWQEN RPDYVNIQLY LSQTDGIQKI IGEKYHALNS RLFIGRPRWK LLFDEIAKYN RGKTVGVFCC GPNSLSKTLH KLSNQNNSYG TRFEYNKESF S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 328-578 of human NOX4 (NP_058627.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu NADPH Oxidase 4

Target: NADPH Oxidase 4 (NOX4)

Andere Bezeichnung: NOX4

Hintergrund: This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.,NOX4,KOX,KOX-1,RENOX,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Drug metabolism,Immunology & Inflammation,Cardiovascular,Blood,Heart,Cardiovascular diseases,Heart disease,NOX4

Molekulargewicht: 6 kDa/25-31 kDa/58-66 kDa

Gen-ID: 50507

UniProt: Q9NPH5

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration