MSH3 Antikörper (AA 617-761)
Kurzübersicht für MSH3 Antikörper (AA 617-761) (ABIN6144059)
Target
Alle MSH3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 617-761
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Sequenz
- FNTSEEHHAD MYRSDLPNPD TLSAELHCWR IKWKHRGKDI ELPSTIYEAL HLPDIKFFPN VYALLKVLCI LPVMKVENER YENGRKRLKA YLRNTLTDQR SSNLALLNIN FDIKHDLDLM VDTYIKLYTS KSELPTDNSE TVENT
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 617-761 of human MSH3 (NP_004696.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- MSH3 (MutS Homolog 3 (MSH3))
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Andere Bezeichnung
- MSH3
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Hintergrund
- The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer.,MSH3,DUP,FAP4,MRP1,Epigenetics & Nuclear Signaling,DNA Damage & Repair,MSH3
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Molekulargewicht
- 127 kDa
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Gen-ID
- 4437
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UniProt
- P20585
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Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
Target
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