LAT Antikörper (AA 28-233)
Kurzübersicht für LAT Antikörper (AA 28-233) (ABIN6143099)
Target
Alle LAT Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 28-233
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Sequenz
- HCHRLPGSYD STSSDSLYPR GIQFKRPHTV APWPPAYPPV TSYPPLSQPD LLPIPRSPQP LGGSHRTPSS RRDSDGANSV ASYENEEPAC EDADEDEDDY HNPGYLVVLP DSTPATSTAA PSAPALSTPG IRDSAFSMES IDDYVNVPES GESAEASLDG SREYVNVSQE LHPGAAKTEP AALSSQEAEE VEEEGAPDYE NLQELN
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 28-233 of human LAT (NP_001014987.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- LAT (Linker For Activation of T Cells (LAT))
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Andere Bezeichnung
- LAT
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Hintergrund
- The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms.,LAT,LAT1,pp36,IMD52,Signal Transduction,G protein signaling,Signal Transduction,Immunology & Inflammation,T Cell Receptor Signaling Pathway,LAT
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Molekulargewicht
- 24 kDa/27 kDa/28 kDa
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Gen-ID
- 27040
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UniProt
- O43561
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Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung
Target
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