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Rekombinanter LAT Antikörper (pTyr191)

LAT Reaktivität: Human WB, ELISA, IHC, IP, IF Wirt: Kaninchen Monoclonal 2E4 unconjugated Recombinant Antibody
Produktnummer ABIN7127705
  • Target Alle LAT Antikörper anzeigen
    LAT (Linker For Activation of T Cells (LAT))
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 19
    • 15
    • 15
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr191
    Reaktivität
    • 134
    • 59
    • 41
    • 1
    • 1
    Human
    Wirt
    • 116
    • 18
    • 2
    • 1
    Kaninchen
    Klonalität
    • 119
    • 18
    Monoklonal
    Konjugat
    • 65
    • 8
    • 8
    • 8
    • 6
    • 6
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Dieser LAT Antikörper ist unkonjugiert
    Applikation
    • 74
    • 40
    • 39
    • 39
    • 18
    • 11
    • 10
    • 9
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Kreuzreaktivität
    Human
    Aufreinigung
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human Phospho-LAT (Y191)
    Klon
    2E4
    Isotyp
    IgG
    Top Product
    Discover our top product LAT Primärantikörper
  • Applikationshinweise
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    LAT (Linker For Activation of T Cells (LAT))
    Andere Bezeichnung
    LAT (LAT Produkte)
    Synonyme
    LAT antikoerper, lat antikoerper, LAT1 antikoerper, pp36 antikoerper, linker for activation of T-cells antikoerper, linker for activation of T cells antikoerper, LAT antikoerper, lat antikoerper, Lat antikoerper
    Hintergrund

    Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

    Aliases: Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT

    UniProt
    O43561
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung
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