KIT Antikörper (AA 25-295)

Produktnummer ABIN6142896

Der Kaninchen Polyklonal Anti-KIT-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, KIT in Proben von Human zu detektieren.

Kurzübersicht für KIT Antikörper (AA 25-295) (ABIN6142896)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-KIT Antikörper

Bindungsspezifität: AA 25-295

Sequenz: SQPSVSPGEP SPPSIHPGKS DLIVRVGDEI RLLCTDPGFV KWTFEILDET NENKQNEWIT EKAEATNTGK YTCTNKHGLS NSIYVFVRDP AKLFLVDRSL YGKEDNDTLV RCPLTDPEVT NYSLKGCQGK PLPKDLRFIP DPKAGIMIKS VKRAYHRLCL HCSVDQEGKS VLSEKFILKV RPAFKAVPVV SVSKASYLLR EGEEFTVTCT IKDVSSSVYS TWKRENSQTK LQEKYNSWHH GDFNYERQAT LTISSARVND SGVFMCYANN T

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-295 of human CD117/c-Kit (NP_000213.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Andere Bezeichnung: KIT

Hintergrund: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.,KIT,C-Kit,CD117,PBT,SCFR,c-kit,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,CD markers,Cytokines,Neuroscience,Cell Type Marker,Stem Cells,Germline Stem Cells,Hematopoietic Progenitors,KIT

Molekulargewicht: 46 kDa/109 kDa

Gen-ID: 3815

UniProt: P10721

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity