VEGFR2/CD309 Antikörper (AA 1150-1250)

Produktnummer ABIN6142817

Der Kaninchen Polyklonal Anti-VEGFR2/CD309-Antikörper wurde für WB validiert. Er ist geeignet, VEGFR2/CD309 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für VEGFR2/CD309 Antikörper (AA 1150-1250) (ABIN6142817)

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VEGFR2/CD309 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-VEGFR2/CD309 Antikörper

Bindungsspezifität: AA 1150-1250

Sequenz: RPTFSELVEH LGNLLQANAQ QDGKDYIVLP ISETLSMEED SGLSLPTSPV SCMEEEEVCD PKFHYDNTAG ISQYLQNSKR KSRPVSVKTF EDIPLEEPEV K

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1150-1250 of human VEGF Receptor 2 (NP_002244.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-VEGFR2/CD309 Antikörper (ABIN6142817)

Yuan, Shan, Tan, Deng, Liu, Wang, Luo, He, Luo, Zhang, Baker, Olson, Qi: "SRC-3 Plays a Critical Role in Human Umbilical Vein Endothelial Cells by Regulating the PI3K/Akt/mTOR Pathway in Preeclampsia." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 25, Issue 5, pp. 748-758, (2018) (PubMed).

Details zu VEGFR2/CD309

Target: VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Andere Bezeichnung: KDR

Hintergrund: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.,CD309,FLK1,VEGFR,VEGFR2,VEGF Receptor 2,KDR,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,VEGF,VEGF Receptors,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,Angiogenic growth factors,Hypoxia,KDR

Molekulargewicht: 75 kDa/79 kDa/151 kDa

Gen-ID: 3791

UniProt: P35968

Pathways: RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling