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VEGFR2/CD309 Antikörper (AA 1150-1250)

Name: VEGFR2/CD309 Antikörper (AA 1150-1250)
Brand: antibodies-online
SKU: ABIN6142817
Price: 722.37 EUR
Availability: InStock

VEGFR2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated

Western blot analysis of extracts of Mouse heart, using VEGF Receptor 2 antibody (ABIN6134816, ABIN6142817, ABIN6142820 and ABIN6221243) at 1:1000 dilution. (VEGFR2/CD309 Antikörper (AA 1150-1250))

Effect of ASC-MV treatment on gene expression in all three kinds of cells. (VEGFR2/CD309 Antikörper (AA 1150-1250))

2 Abbildungen

(1 reference)

Produktnummer ABIN6142817

Datenblatt (PDF)

Target Alle VEGFR2/CD309 (VEGFR2) Antikörper anzeigen

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
Bindungsspezifität
37

34

27

23

20

16

11

10

10

8

8

6

5

5

5

4

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1150-1250
Reaktivität
294

184

128

9

5

3

3

3

3

1

1

1

1

1

1

1

1

1

1

1
Human
Wirt
274

60

24

1

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
266

95
Polyklonal
Konjugat
166

30

18

13

10

9

9

7

7

7

7

7

5

5

5

5

5

5

5

5

5

5

5

3

2

2

2

1

1

1

1

1

1

1
Dieser VEGFR2/CD309 Antikörper ist unkonjugiert
Applikation
214

117

98

85

64

25

24

18

13

13

11

9

7

7

7

4

3

2

2

2

2

1

1

1
Western Blotting (WB)

Sequenz

RPTFSELVEH LGNLLQANAQ QDGKDYIVLP ISETLSMEED SGLSLPTSPV SCMEEEEVCD PKFHYDNTAG ISQYLQNSKR KSRPVSVKTF EDIPLEEPEV K

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Polyclonal Antibodies

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1150-1250 of human VEGF Receptor 2 (NP_002244.1).

Isotyp

IgG

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Applikationshinweise

WB,1:500 - 1:2000

Kommentare

HIGH QUALITY

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Yuan, Shan, Tan, Deng, Liu, Wang, Luo, He, Luo, Zhang, Baker, Olson, Qi: "SRC-3 Plays a Critical Role in Human Umbilical Vein Endothelial Cells by Regulating the PI3K/Akt/mTOR Pathway in Preeclampsia." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 25, Issue 5, pp. 748-758, (2018) (PubMed).
Target

VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))

Andere Bezeichnung

KDR (VEGFR2 Produkte)

Hintergrund

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.,CD309,FLK1,VEGFR,VEGFR2,VEGF Receptor 2,KDR,Cancer,Invasion and Metastasis,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,VEGF,VEGF Receptors,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Hematopoietic Progenitors,Cardiovascular,Angiogenesis,Angiogenic growth factors,Hypoxia,KDR

Molekulargewicht

75 kDa/79 kDa/151 kDa

Gen-ID

3791

UniProt

P35968

Pathways

RTK Signalweg, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling