IL5RA Antikörper (AA 20-335)
Kurzübersicht für IL5RA Antikörper (AA 20-335) (ABIN6142402)
Target
Alle IL5RA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 20-335
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Sequenz
- ADLLPDEKIS LLPPVNFTIK VTGLAQVLLQ WKPNPDQEQR NVNLEYQVKI NAPKEDDYET RITESKCVTI LHKGFSASVR TILQNDHSLL ASSWASAELH APPGSPGTSI VNLTCTTNTT EDNYSRLRSY QVSLHCTWLV GTDAPEDTQY FLYYRYGSWT EECQEYSKDT LGRNIACWFP RTFILSKGRD WLAVLVNGSS KHSAIRPFDQ LFALHAIDQI NPPLNVTAEI EGTRLSIQWE KPVSAFPIHC FDYEVKIHNT RNGYLQIEKL MTNAFISIID DLSKYDVQVR AAVSSMCREA GLWSEWSQPI YVGFSR
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-335 of human IL5RA (NP_783855.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- IL5RA (Interleukin 5 Receptor, alpha (IL5RA))
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Andere Bezeichnung
- IL5RA
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Hintergrund
- The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.,IL5RA,CD125,CDw125,HSIL5R3,IL5R,Immunology & Inflammation,CD markers,Cytokines,Interleukins,Cell Intrinsic Innate Immunity Signaling Pathway,IL5RA
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Molekulargewicht
- 23 kDa/37 kDa/42 kDa/47 kDa
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Gen-ID
- 3568
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UniProt
- Q01344
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Pathways
- JAK-STAT Signalweg
Target
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