EIF4A1 Antikörper (AA 1-406)

Produktnummer ABIN6140076

Produktdetails anti-EIF4A1 Antikörper

Target: EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))

Bindungsspezifität: AA 1-406

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequenz: MSASQDSRSR DNGPDGMEPE GVIESNWNEI VDSFDDMNLS ESLLRGIYAY GFEKPSAIQQ RAILPCIKGY DVIAQAQSGT GKTATFAISI LQQIELDLKA TQALVLAPTR ELAQQIQKVV MALGDYMGAS CHACIGGTNV RAEVQKLQME APHIIVGTPG RVFDMLNRRY LSPKYIKMFV LDEADEMLSR GFKDQIYDIF QKLNSNTQVV LLSATMPSDV LEVTKKFMRD PIRILVKKEE LTLEGIRQFY INVEREEWKL DTLCDLYETL TITQAVIFIN TRRKVDWLTE KMHARDFTVS AMHGDMDQKE RDVIMREFRS GSSRVLITTD LLARGIDVQQ VSLVINYDLP TNRENYIHRI GRGGRFGRKG VAINMVTEED KRTLRDIETF YNTSIEEMPL NVADLI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-406 of human eIF4A1 (NP_001407.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:20 - 1:50,IP,1:20 - 1:50

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-EIF4A1 Antikörper (ABIN6140076)

Yang, Hu, Fan, Zhang, Zhong, Guo, Qin, Chen: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).

Hu, Wang, Tang, Yang, Qin, Chen: "Inclusion bodies of human parainfluenza virus type 3 inhibit antiviral stress granule formation by shielding viral RNAs." in: PLoS pathogens, Vol. 14, Issue 3, pp. e1006948, (2018) (PubMed).

Details zu EIF4A1

Target: EIF4A1 (Eukaryotic Translation Initiation Factor 4A1 (EIF4A1))

Andere Bezeichnung: EIF4A1 (EIF4A1 Produkte)

Synonyme: DDX2A antikoerper, EIF-4A antikoerper, EIF4A antikoerper, eIF-4A-I antikoerper, eIF4A-I antikoerper, BM-010 antikoerper, Ddx2a antikoerper, Eif4 antikoerper, ddx2a antikoerper, eif-4a antikoerper, eif4a antikoerper, eif4a1 antikoerper, fb49a04 antikoerper, im:7143023 antikoerper, wu:fb20a10 antikoerper, wu:fb49a04 antikoerper, wu:fc76a02 antikoerper, wu:fc96c01 antikoerper, wu:fd15g03 antikoerper, eukaryotic translation initiation factor 4A1 antikoerper, eukaryotic translation initiation factor 4A1 L homeolog antikoerper, eukaryotic initiation factor 4A-I antikoerper, eukaryotic translation initiation factor 4A1A antikoerper, EIF4A1 antikoerper, Eif4a1 antikoerper, eif4a1.L antikoerper, eif4a1 antikoerper, LOC695050 antikoerper, eif4a1a antikoerper

Hintergrund: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.,EIF4A1,DDX2A,EIF-4A,EIF4A,eIF-4A-I,eIF4A-I,Epigenetics & Nuclear Signaling,RNA Binding,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Immunology & Inflammation,EIF4A1

Molekulargewicht: 39 kDa/46 kDa

Gen-ID: 1973

UniProt: P60842