desert Hedgehog Antikörper (AA 199-396)

Produktnummer ABIN6139585

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch desert Hedgehog in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für desert Hedgehog Antikörper (AA 199-396) (ABIN6139585)

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser desert Hedgehog Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-desert Hedgehog Antikörper

Bindungsspezifität: AA 199-396

Sequenz: CFPGNATVRL WSGERKGLRE LHRGDWVLAA DASGRVVPTP VLLFLDRDLQ RRASFVAVET EWPPRKLLLT PWHLVFAARG PAPAPGDFAP VFARRLRAGD SVLAPGGDAL RPARVARVAR EEAVGVFAPL TAHGTLLVND VLASCYAVLE SHQWAHRAFA PLRLLHALGA LLPGGAVQPT GMHWYSRLLY RLAEELLG

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 199-396 of human DHH (NP_066382.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu desert Hedgehog

Target: desert Hedgehog (DHH) (Desert Hedgehog (DHH))

Andere Bezeichnung: DHH

Substanzklasse: Species

Hintergrund: This gene encodes a member of the hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.,DHH,GDXYM,HHG-3,SRXY7,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Stem Cells,DHH

Molekulargewicht: 43 kDa

Gen-ID: 50846

UniProt: O43323

Pathways: Hedgehog Signalweg