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desert Hedgehog Antikörper (Center)

DHH Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2854606
  • Target Alle desert Hedgehog (DHH) Antikörper anzeigen
    desert Hedgehog (DHH) (Desert Hedgehog (DHH))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    Reaktivität
    • 43
    • 14
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 44
    • 4
    • 2
    • 2
    Kaninchen
    Klonalität
    • 48
    • 4
    Polyklonal
    Konjugat
    • 28
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser desert Hedgehog Antikörper ist unkonjugiert
    Applikation
    • 40
    • 23
    • 10
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus, Ratte (Rattus)
    Kreuzreaktivität (Details)
    Mouse (98 %), Rat (98 %)
    Produktmerkmale
    Rabbit polyclonal antibody to Dhh (desert hedgehog homolog (Drosophila))
    Dhh antibody [N3C3]
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Immunogen
    Recombinant protein encompassing a sequence within the center region of human Dhh. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product DHH Primärantikörper
  • Applikationshinweise
    Suggested dilution Reference Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:5000-1:20000*
    Kommentare

    Positive Control: 293T , A431 , Jurkat , Raji

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.95 mg/mL
    Buffer
    0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    Konservierungsmittel
    Thimerosal (Merthiolate)
    Vorsichtsmaßnahmen
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    desert Hedgehog (DHH) (Desert Hedgehog (DHH))
    Andere Bezeichnung
    Dhh (DHH Produkte)
    Synonyme
    GDXYM antikoerper, HHG-3 antikoerper, SRXY7 antikoerper, C78960 antikoerper, Xchh antikoerper, chh antikoerper, chh-a antikoerper, dhh antikoerper, dhh-1 antikoerper, dhh-A antikoerper, hh4 antikoerper, x-chh antikoerper, desert hedgehog antikoerper, desert hedgehog L homeolog antikoerper, desert hedgehog S homeolog antikoerper, DHH antikoerper, dhh antikoerper, Dhh antikoerper, dhh.L antikoerper, dhh.S antikoerper
    Substanzklasse
    Species
    Hintergrund
    This gene encodes a member of the Hedgehog family. The hedgehog gene family encodes signaling molecules that play an important role in regulating morphogenesis. This protein is predicted to be made as a precursor that is autocatalytically cleaved, the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the organism. Defects in this protein have been associated with partial gonadal dysgenesis (PGD) accompanied by minifascicular polyneuropathy. This protein may be involved in both male gonadal differentiation and perineurial development.

    Cellular Localization: Desert hedgehog protein N-product: Cell membrane, Lipid-anchor, Extracellular side , Desert hedgehog protein C-product: Secreted , extracellular space , Desert hedgehog protein N-product: Cell membrane , Desert hedgehog protein C-product: Secreted , extra
    Molekulargewicht
    44 kDa
    Gen-ID
    50846
    Pathways
    Hedgehog Signalweg
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