COPS6 Antikörper (AA 58-327)
Kurzübersicht für COPS6 Antikörper (AA 58-327) (ABIN6138885)
Target
Alle COPS6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 58-327
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Sequenz
- MRSQEGRPVQ VIGALIGKQE GRNIEVMNSF ELLSHTVEEK IIIDKEYYYT KEEQFKQVFK ELEFLGWYTT GGPPDPSDIH VHKQVCEIIE SPLFLKLNPM TKHTDLPVSV FESVIDIING EATMLFAELT YTLATEEAER IGVDHVARMT ATGSGENSTV AEHLIAQHSA IKMLHSRVKL ILEYVKASEA GEVPFNHEIL REAYALCHCL PVLSTDKFKT DFYDQCNDVG LMAYLGTITK TCNTMNQFVN KFNVLYDRQG IGRRMRGLFF
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 58-327 of human COPS6 (NP_006824.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
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Andere Bezeichnung
- COPS6
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Hintergrund
- The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.,COPS6,CSN6,MOV34-34KD,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,COPS6
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Molekulargewicht
- 36 kDa
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Gen-ID
- 10980
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UniProt
- Q7L5N1
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Pathways
- Zellzyklus
Target
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