CENPJ Antikörper (AA 1069-1338)

Produktnummer ABIN6138409

Der Kaninchen Polyklonal Anti-CENPJ-Antikörper wurde für WB validiert. Er ist geeignet, CENPJ in Proben von Human zu detektieren.

Kurzübersicht für CENPJ Antikörper (AA 1069-1338) (ABIN6138409)

Target: CENPJ (Centromere Protein J (CENPJ))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CENPJ Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CENPJ Antikörper

Bindungsspezifität: AA 1069-1338

Sequenz: DKLANTSVRF QNSQISSGTQ VEKYKKNYLP MQGNPPRRSK SAPPRDLGNL DKGQAASPRE PLEPLNFPDP EYKEEEEDQD IQGEISHPDG KVEKVYKNGC RVILFPNGTR KEVSADGKTI TVTFFNGDVK QVMPDQRVIY YYAAAQTTHT TYPEGLEVLH FSSGQIEKHY PDGRKEITFP DQTVKNLFPD GQEESIFPDG TIVRVQRDGN KLIEFNNGQR ELHTAQFKRR EYPDGTVKTV YANGHQETKY RSGRIRVKDK EGNVLMDTEL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1069-1338 of human CENPJ (NP_060921.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CENPJ

Target: CENPJ (Centromere Protein J (CENPJ))

Andere Bezeichnung: CENPJ

Hintergrund: This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene.,CENPJ,BM032,CENP-J,CPAP,LAP,LIP1,MCPH6,SASS4,SCKL4,Sas-4,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,Centromere,CENPJ

Molekulargewicht: 124 kDa/153 kDa

Gen-ID: 55835

UniProt: Q9HC77

Pathways: M Phase