CTLA4 Antikörper
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- Target Alle CTLA4 Antikörper anzeigen
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- Fragment
- F(ab')2 fragment
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CTLA4 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), ELISA, Functional Studies (Func)
- Spezifität
- CTLA-4 expressed on activated T cells.
- Aufreinigung
- Gel filtration
- Sterilität
- 0.1 μm filtered
- Immunogen
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Stimulated human PBL’,s and human CD152 Ig fusion protein.
Type of Immunogen: Fusion protein - Klon
- ANC152-2-8H5
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CTLA4 Primärantikörper
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- Applikationshinweise
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Approved: ELISA, Flo, Func
Usage: Function: ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro. ANC152.2 can bind to intracellular CD152 in fixed permeabolized cells. The F(ab')2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- 50 mM sodium phosphate, pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride. Product was 0.1 μm filtered, vialed under aseptic conditions. No preservative added
- Konservierungsmittel
- Without preservative
- Handhabung
- Do not freeze. Open under aseptic conditions.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 4°C. Do not freeze. Open under aseptic conditions.
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- Target
- CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))
- Andere Bezeichnung
- CTLA4 / CD152 (CTLA4 Produkte)
- Hintergrund
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Name/Gene ID: CTLA4
Synonyms: CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform - Gen-ID
- 1493
- UniProt
- P16410
- Pathways
- Cancer Immune Checkpoints
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