CTLA4 Antikörper (Biotin)

Produktnummer ABIN610401

Dieser Anti-CTLA4 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CTLA4 in FACS, ELISA und Func. Geeignet für Human.

Kurzübersicht für CTLA4 Antikörper (Biotin) (ABIN610401)

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CTLA4 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS), ELISA, Functional Studies (Func)

Klon: ANC152-2-8H5

Produktdetails anti-CTLA4 Antikörper (Biotin)

Spezifität: CTLA-4 expressed on activated T cells.

Aufreinigung: Protein A purified

Immunogen: Stimulated human PBL’,s and human CD152 Ig fusion protein.

Type of Immunogen: Fusion protein

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo, Func

Usage: Function: ANC152.2 blocks binding of CD152 (CTLA-4) Ig fusion protein to its CD80/CD86 receptor, and has been reported to modulate suppressive function of human T Regulatory Cells in Vitro. ANC152.2 can bind to intracellular CD152 in fixed permeabolized cells. The F(ab')2 form has been used to inhibit proliferation of activated T cells in vitro in a cholera toxin model. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 5 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Do not freeze.

Details zu CTLA4

Target: CTLA4 (Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4))

Andere Bezeichnung: CTLA4 / CD152

Hintergrund: Name/Gene ID: CTLA4

Synonyms: CTLA4, CD152, CELIAC3, CD152 antigen, CTLA-4, Celiac disease 3, IDDM12, GRD4, GSE, CD152 isoform

Gen-ID: 1493

UniProt: P16410

Pathways: Cancer Immune Checkpoints