Caveolin-1 Antikörper

Produktnummer ABIN5960477

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Caveolin-1 in WB, ELISA, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für Caveolin-1 Antikörper (ABIN5960477)

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caveolin-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Caveolin-1 Antikörper

Spezifität: BSCL3,CAV,CAV1,CAV1,caveolae protein,22 kD,caveolin 1 alpha isoform,caveolin 1 beta isoform,Caveolin 1 caveolae protein 22  kDa,Caveolin-1,Caveolin1,cell growth-inhibiting protein 32,CGL3,LCCNS,MSTP085,OTTHUMP00000025031,PPH3,VIP 21,VIP21

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the C-terminal region of human Caveolin-1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-2000, IHC 1:50-300, IF 1:50-300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Caveolin-1

Target: Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))

Andere Bezeichnung: CAV1

Hintergrund: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Molekulargewicht: 20kDa

Gen-ID: 857

UniProt: Q03135

Pathways: Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals