PKC zeta Antikörper (Thr410)

Produktnummer ABIN5957395

Der Kaninchen Polyklonal anti-PKC zeta Antikörper (ABIN5957395) detektiert spezifisch PKC zeta in WB, ELISA, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PKC zeta Antikörper (Thr410) (ABIN5957395)

Target: PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKC zeta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PKC zeta Antikörper

Bindungsspezifität: Thr410

Spezifität: 14-3-3-zetaisoform,AI098070,aPKCzeta,C80388,EC 2.7.11.13,KPCZ,nPKC zeta,nPKC-zeta,OTTHUMP00000001368,OTTHUMP00000044160,PKC 2,PKC ZETA,PKC2,Pkcz,PKCZETA,PKM-zeta,included,PRKCZ,Protein kinase C zeta,Protein kinase C zeta form,Protein kinase C zeta type,r14-3-3,R74924,zetaPKC

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human PKC zeta around the non-phosphorylation site of Thr410.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PKC zeta

Target: PKC zeta (PRKCZ) (Protein Kinase C, zeta (PRKCZ))

Andere Bezeichnung: PKC zeta

Hintergrund: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.

Molekulargewicht: 68kDa

Gen-ID: 5590

UniProt: Q05513

Pathways: NF-kappaB Signalweg, RTK Signalweg, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Membrane, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling