MCL-1 Antikörper (pSer159)

Produktnummer ABIN5957044

Der Kaninchen Polyklonal anti-MCL-1 Antikörper (ABIN5957044) detektiert spezifisch MCL-1 in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für MCL-1 Antikörper (pSer159) (ABIN5957044)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MCL-1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-MCL-1 Antikörper

Bindungsspezifität: pSer159

Spezifität: Bcl 2 related protein EAT/mcl1,Bcl-2-like protein 3,Bcl-2-related protein EAT/mcl1,BCL2 related,Bcl2-L-3,BCL2L3,EAT,Induced myeloid leukemia cell differentiation protein Mcl 1,Induced myeloid leukemia cell differentiation protein Mcl-1,MCL 1,MCL1,MCL1-ES,mcl1/EAT,MCL1,MCL1L,MCL1S,MGC104264,MGC1839,Myeloid Cell Leukemia 1,Myeloid cell leukemia ES,Myeloid cell leukemia sequence 1,Myeloid cell leukemia sequence 1 BCL2 related,Myeloid cell leukemia sequence 1 isoform 1,OTTHUMP00000032794,OTTHUMP00000032795,TM

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human Mcl-1 around the phosphorylation site of S159.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF 1:200-1:1000, ELISA 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Andere Bezeichnung: Mcl-1

Hintergrund: This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Molekulargewicht: 37kDa

Gen-ID: 4170

UniProt: Q07820

Pathways: MAPK Signalweg