CD46 Antikörper (AA 35-313)

Produktnummer ABIN5776214

Dieser Anti-CD46 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von CD46 in WB, FACS, IHC, IF, ELISA und ICC. Geeignet für Human.

Kurzübersicht für CD46 Antikörper (AA 35-313) (ABIN5776214)

Target: CD46

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD46 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Klon: AT2G9

Produktdetails anti-CD46 Antikörper

Bindungsspezifität: AA 35-313

Verwendungszweck: Human CD46 antibody

Aufreinigung: Purified

Immunogen: Recombinant human CD46 (35-313aa) purified from E. coli

Isotyp: IgG2a kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu CD46

Target: CD46

Andere Bezeichnung: CD46

Hintergrund: Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types.

NCBI Accession: NP_758860

Pathways: Regulation of Actin Filament Polymerization