CD46 Antikörper (AA 35-313)
Kurzübersicht für CD46 Antikörper (AA 35-313) (ABIN5776214)
Target
Alle CD46 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 35-313
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Immunogen
- Recombinant human CD46 (35-313aa) purified from E. coli
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Isotyp
- IgG2a kappa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- CD46
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Andere Bezeichnung
- CD46
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Hintergrund
- Membrane Cofactor Protein (CD46) is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 regulates the complement cascade by inhibiting C3b and C4b deposited on self tissue. This protein is a cofactor that binds to C3b and C4b, allowing their degradation by a plasma serine protease called factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is implicated in the development and/or progression of selected cancer types.
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NCBI Accession
- NP_758860
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Pathways
- Regulation of Actin Filament Polymerization
Target
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