ING2 Antikörper (AA 1-280)

Produktnummer ABIN5776013

Dieser Anti-ING2 Antikörper ist ein Maus Monoklonal Antikörper zur Detektion von ING2 in WB, ELISA, IF und ICC. Geeignet für Human.

Kurzübersicht für ING2 Antikörper (AA 1-280) (ABIN5776013)

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ING2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: AT39E5

Produktdetails anti-ING2 Antikörper

Bindungsspezifität: AA 1-280

Verwendungszweck: Human ING2 antibody

Aufreinigung: Purified

Immunogen: Recombinant human ING2 (1-280aa) purified from E. coli

Isotyp: IgG1b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu ING2

Target: ING2 (Inhibitor of Growth Family, Member 2 (ING2))

Andere Bezeichnung: ING2

Hintergrund: ING2 is a member of the inhibitor of growth (ING) family. Members of the ING family associate with and modulate the activity of histone acetyltransferase (HAT) and histone deacetylase (HDAC) complexes and function in DNA repair and apoptosis. This protein seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Also, It is component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides.

NCBI Accession: NP_001555

Pathways: Chromatin Binding, Autophagie, Negative Regulation of intrinsic apoptotic Signaling