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ING2 Antikörper (C-Term)

ING2 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6257713
  • Target Alle ING2 Antikörper anzeigen
    ING2 (Inhibitor of Growth Family, Member 2 (ING2))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 32
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus
    Wirt
    • 26
    • 5
    • 1
    Kaninchen
    Klonalität
    • 28
    • 4
    Polyklonal
    Konjugat
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ING2 Antikörper ist unkonjugiert
    Applikation
    • 24
    • 18
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    ING2 Antibody detects endogenous levels of total ING2.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
    Aufreinigung
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human ING2, corresponding to a region within C-terminal amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ING2 Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    ING2 (Inhibitor of Growth Family, Member 2 (ING2))
    Andere Bezeichnung
    ING2 (ING2 Produkte)
    Synonyme
    ING1L antikoerper, p33ING2 antikoerper, 2810011M06Rik antikoerper, Ing1l antikoerper, Ing2b antikoerper, P33ING2 antikoerper, ING2 antikoerper, INGX antikoerper, wu:fe11c08 antikoerper, zgc:92346 antikoerper, ING1Lp antikoerper, ing2 antikoerper, xing2 antikoerper, inhibitor of growth family member 2 antikoerper, inhibitor of growth family, member 2 antikoerper, inhibitor of growth family member 2 S homeolog antikoerper, inhibitor of growth family member 2 L homeolog antikoerper, ING2 antikoerper, Ing2 antikoerper, ing2.S antikoerper, ing2 antikoerper, ing2.L antikoerper
    Hintergrund

    Description: Seems to be involved in p53/TP53 activation and p53/TP53-dependent apoptotic pathways, probably by enhancing acetylation of p53/TP53. Component of a mSin3A-like corepressor complex, which is probably involved in deacetylation of nucleosomal histones. ING2 activity seems to be modulated by binding to phosphoinositides (PtdInsPs).

    Gene: ING2

    Molekulargewicht
    33 kDa
    Gen-ID
    3622
    UniProt
    Q9H160
    Pathways
    Chromatin Binding, Autophagie, Negative Regulation of intrinsic apoptotic Signaling
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