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Annexin V Antikörper (Biotin)

ANXA5 Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal Biotin
Produktnummer ABIN576509
  • Target Alle Annexin V (ANXA5) Antikörper anzeigen
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    Reaktivität
    • 117
    • 58
    • 44
    • 12
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 124
    • 27
    Maus
    Klonalität
    • 119
    • 30
    Monoklonal
    Konjugat
    • 71
    • 22
    • 20
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Annexin V Antikörper ist konjugiert mit Biotin
    Applikation
    • 104
    • 47
    • 40
    • 20
    • 20
    • 17
    • 17
    • 14
    • 11
    • 9
    • 5
    • 4
    • 2
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Spezifität
    Recognizes human Annexin V, a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). Clone VAA-33 has been reported to work in western blotting applications.
    Aufreinigung
    Protein G purified
    Immunogen
    Recombinant Annexin V.

    Type of Immunogen: Recombinant protein
    Isotyp
    IgG2a
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  • Applikationshinweise
    Approved: ELISA, Flo

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Tris-buffered saline, 1 % BSA, 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target
    Annexin V (ANXA5) (Annexin A5 (ANXA5))
    Andere Bezeichnung
    ANXA5 / Annexin V (ANXA5 Produkte)
    Hintergrund
    Name/Gene ID: ANXA5

    Synonyms: ANXA5, ANX5, Anchorin CII, Calphobindin I, CBP-I, ENX2, PP4, RPRGL3, Lipocortin V, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha, PAP-I, Annexin A5, Annexin V, Annexin-5, Endonexin II
    Gen-ID
    308
    UniProt
    P08758
    Pathways
    Apoptose
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