Annexin V Antikörper (Biotin)
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- Target Alle Annexin V (ANXA5) Antikörper anzeigen
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Annexin V Antikörper ist konjugiert mit Biotin
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Applikation
- ELISA, Flow Cytometry (FACS)
- Spezifität
- Recognizes human Annexin V, a phospholipid binding protein which binds with high affinity and selectivity to phosphatidylserine (PS), in the presence of calcium. The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell by phagocytosis. Detection of PS using Annexin V therefore provides a reliable diagnostic tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc). Clone VAA-33 has been reported to work in western blotting applications.
- Aufreinigung
- Protein G purified
- Immunogen
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Recombinant Annexin V.
Type of Immunogen: Recombinant protein - Isotyp
- IgG2a
- Top Product
- Discover our top product ANXA5 Primärantikörper
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- Applikationshinweise
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Approved: ELISA, Flo
Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Tris-buffered saline, 1 % BSA, 0.02 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- 4°C or -20°C, Avoid freeze-thaw cycles.
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- Target
- Annexin V (ANXA5) (Annexin A5 (ANXA5))
- Andere Bezeichnung
- ANXA5 / Annexin V (ANXA5 Produkte)
- Hintergrund
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Name/Gene ID: ANXA5
Synonyms: ANXA5, ANX5, Anchorin CII, Calphobindin I, CBP-I, ENX2, PP4, RPRGL3, Lipocortin V, Thromboplastin inhibitor, VAC-alpha, Vascular anticoagulant-alpha, PAP-I, Annexin A5, Annexin V, Annexin-5, Endonexin II - Gen-ID
- 308
- UniProt
- P08758
- Pathways
- Apoptose
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