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EGFR Antikörper (Extracellular Domain) (PE)

EGFR Reaktivität: Human FACS Wirt: Ratte Monoclonal ICR10 PE

Produktnummer ABIN576424

Datenblatt (PDF)

Target Alle EGFR Antikörper anzeigen

EGFR (Epidermal Growth Factor Receptor (EGFR))
Bindungsspezifität
39

38

31

31

29

28

27

26

25

22

21

18

16

16

16

15

15

15

11

11

10

9

9

9

8

8

7

6

5

5

5

4

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

3
Extracellular Domain
Reaktivität
759

299

287

25

25

24

20

14

8

3

2

2

1

1

1

1

1

1
Human
Wirt
581

178

13

13

5

2

1

1
Ratte
Passende Sekundärantikörper
Klonalität
543

246

2
Monoklonal
Konjugat
414

58

29

22

19

18

18

17

16

16

16

12

10

10

10

10

10

10

10

10

10

8

8

5

4

4

4

4

4

2

1

1

1

1

1

1
Dieser EGFR Antikörper ist konjugiert mit PE
Applikation
538

250

151

151

128

102

99

93

82

46

37

34

34

19

11

8

6

4

4

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Flow Cytometry (FACS)

Spezifität

Recognizes the human epidermal growth factor receptor (EGF-R), which is over expressed in a high proportion of breast cancer cells and in a range of other carcinomas. High level expression of EGFR is often associated with advanced disease and poor prognosis. Binds to epitope B from EGFR and has an affinity of 6.7 x 10-9 M.

Aufreinigung

Protein G purified

Immunogen

Extracellular domain of human EGF-receptor from head and neck carcinoma.

Type of Immunogen: Recombinant protein

Klon

ICR10

Isotyp

IgG2a

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EGFR Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (AA 1021-1210) antibody
EGFR Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Epidermal Growth Factor Receptor (EGFR) (C-Term) antibody
EGFR Reaktivität: Human, Ratte WB, ELISA, IHC, IP Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Approved: Flo (1:1)

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare

Target Species of Antibody: Human

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Lyophilized

Rekonstitution

Reconstitute with 1 mL distilled water.

Konzentration

Lot specific

Buffer

Lyophilized powder from PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA, 5 % sucrose.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Protect from light.

Lagerung

4 °C

Informationen zur Lagerung

Store at 4°C. Do not freeze. Protect from light.
Target

EGFR (Epidermal Growth Factor Receptor (EGFR))

Andere Bezeichnung

EGFR (EGFR Produkte)

Hintergrund

Name/Gene ID: EGFR
Subfamily: EGF Receptor
Family: Protein Kinase

Synonyms: EGFR, EGFf receptor, ERBB, ERBB1, MENA, PIG61, Proto-oncogene c-ErbB-1, V-erb-b homolog, EGF-R, HER1

Gen-ID

1956

Pathways

NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine