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CD42a Antikörper (APC)

GP9 Reaktivität: Human, Hund FACS Wirt: Maus Monoclonal GR-P APC
Produktnummer ABIN5710576
  • Target Alle CD42a (GP9) Antikörper anzeigen
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    Reaktivität
    • 60
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Hund
    Wirt
    • 41
    • 22
    Maus
    Klonalität
    • 43
    • 20
    Monoklonal
    Konjugat
    • 26
    • 9
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD42a Antikörper ist konjugiert mit APC
    Applikation
    • 26
    • 24
    • 19
    • 14
    • 13
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.
    Kreuzreaktivität (Details)
    Human, Canine (Dog)
    Aufreinigung
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    Human acute lymphoblastic leukemia cells
    Klon
    GR-P
    Isotyp
    IgG1
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    Discover our top product GP9 Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Target
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    Andere Bezeichnung
    CD42a (GP9 Produkte)
    Synonyme
    cd42a antikoerper, gpix antikoerper, GP9 antikoerper, GPIX antikoerper, Cd42 antikoerper, CD42a antikoerper, glycoprotein IX platelet antikoerper, glycoprotein IX platelet L homeolog antikoerper, glycoprotein IX (platelet) antikoerper, glycoprotein 9 (platelet) antikoerper, GP9 antikoerper, gp9.L antikoerper, Gp9 antikoerper
    Hintergrund
    Glycoprotein IX platelet,CD42a, also known as glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.,GPIX, GP9
    Gen-ID
    2815
    UniProt
    P14770
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