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CD42a Antikörper

GP9 Reaktivität: Human, Hund FACS Wirt: Maus Monoclonal GR-P unconjugated
Produktnummer ABIN1981875
  • Target Alle CD42a (GP9) Antikörper anzeigen
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    Reaktivität
    • 60
    • 12
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Hund
    Wirt
    • 41
    • 22
    Maus
    Klonalität
    • 43
    • 20
    Monoklonal
    Konjugat
    • 25
    • 9
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD42a Antikörper ist unkonjugiert
    Applikation
    • 26
    • 24
    • 19
    • 14
    • 13
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes an extracellular epitope of CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.
    Kreuzreaktivität (Details)
    Human, Canine (Dog)
    Aufreinigung
    Purified by protein-A affinity chromatography.
    Reinheit
    > 95 % (by SDS-PAGE)
    Immunogen
    Human acute lymphoblastic leukemia cells
    Klon
    GR-P
    Isotyp
    IgG1
    Top Product
    Discover our top product GP9 Primärantikörper
  • Applikationshinweise
    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze. Do not use after expiration date stamped on vial label.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Do not freeze.
  • Din, Aftab, Jubb, Carnegy, Lyall, Sarma, Newby, Flapan: "Effect of moderate walnut consumption on lipid profile, arterial stiffness and platelet activation in humans." in: European journal of clinical nutrition, Vol. 65, Issue 2, pp. 234-9, (2011) (PubMed).

    Harding, Din, Sarma, Josephs, Fox, Newby: "Promotion of proinflammatory interactions between platelets and monocytes by unfractionated heparin." in: Heart (British Cardiac Society), Vol. 92, Issue 11, pp. 1635-8, (2006) (PubMed).

    Brown, Clarke, Magowan, Sanderson, Savill: "Constitutive death of platelets leading to scavenger receptor-mediated phagocytosis. A caspase-independent cell clearance program." in: The Journal of biological chemistry, Vol. 275, Issue 8, pp. 5987-96, (2000) (PubMed).

  • Target
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    Andere Bezeichnung
    CD42a (GP9 Produkte)
    Synonyme
    cd42a antikoerper, gpix antikoerper, GP9 antikoerper, GPIX antikoerper, Cd42 antikoerper, CD42a antikoerper, glycoprotein IX platelet antikoerper, glycoprotein IX platelet L homeolog antikoerper, glycoprotein IX (platelet) antikoerper, glycoprotein 9 (platelet) antikoerper, GP9 antikoerper, gp9.L antikoerper, Gp9 antikoerper
    Hintergrund
    Glycoprotein IX platelet,CD42a, also known as glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.,GPIX, GP9
    Gen-ID
    2815
    UniProt
    P14770
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