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CD42a Antikörper (PE)

GP9 Reaktivität: Human, Hund FACS Wirt: Maus Monoclonal GR-P PE
Produktnummer ABIN5665750
$484.24
Zzgl. Versandkosten $45.00
100 tests
Lieferung in 5 bis 7 Werktagen
  • Target Alle CD42a (GP9) Antikörper anzeigen
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    Reaktivität
    • 68
    • 13
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Hund
    Wirt
    • 45
    • 26
    Maus
    Klonalität
    • 48
    • 23
    Monoklonal
    Konjugat
    • 28
    • 10
    • 7
    • 6
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD42a Antikörper ist konjugiert mit PE
    Applikation
    • 31
    • 27
    • 23
    • 14
    • 14
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody GR-P (also known as GRP-P) recognizes CD42a (glycoprotein 9), a 22 kDa transmembrane protein constitutively expressed on megakaryocytes and platelets.
    HLDA IV., WS Code P 35
    Kreuzreaktivität (Details)
    Human, Canine (Dog)
    Immunogen
    Human acute lymphoblastic leukemia cells
    Klon
    GR-P
    Isotyp
    IgG1
  • Applikationshinweise
    The reagent is designed for Flow Cytometry analysis of human blood cells using 10 μ,l reagent / 100 μ,l of whole blood or 106 cells in a suspension.The content of a vial (1 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    The reagent is provided in stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light. Do not use after expiration date stamped on vial label.
  • Target
    CD42a (GP9) (Glycoprotein IX (Platelet) (GP9))
    Andere Bezeichnung
    CD42a (GP9 Produkte)
    Synonyme
    cd42a, gpix, GP9, GPIX, Cd42, CD42a, glycoprotein IX platelet, glycoprotein IX platelet L homeolog, glycoprotein IX (platelet), glycoprotein 9 (platelet), GP9, gp9.L, Gp9
    Hintergrund
    CD42a, also known as Glycoprotein 9 (GPIX), composes together with GPIb alpha, GPIb beta and GPV the GPIb-IX-V receptor complex critical in the process of platelet-rich thrombus formation by tethering the platelet to a thrombogenic surface. CD42b binds to von Willebrand factor (VWF) exposed at a site of vascular injury, as well as to thrombin, coagulation factors XI and XII, high molecular wight kininogen, TSP-1, integrin Mac-1 and P-selectin. Defects in the gene encoding CD42a are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
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