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beta Catenin Antikörper

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch beta Catenin in IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN5707937

Kurzübersicht für beta Catenin Antikörper (ABIN5707937)

Target

Alle beta Catenin (CATNB) Antikörper anzeigen
beta Catenin (CATNB) (Catenin, beta (CATNB))

Reaktivität

  • 390
  • 251
  • 229
  • 32
  • 23
  • 22
  • 20
  • 20
  • 7
  • 5
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 284
  • 114
  • 4
  • 1
  • 1
Kaninchen

Klonalität

  • 264
  • 138
  • 2
Monoklonal

Konjugat

  • 156
  • 25
  • 13
  • 11
  • 10
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 8
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 1
  • 1
  • 1
Dieser beta Catenin Antikörper ist unkonjugiert

Applikation

  • 256
  • 172
  • 138
  • 120
  • 118
  • 85
  • 72
  • 58
  • 51
  • 48
  • 46
  • 32
  • 8
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

CTNNB1-2030R
  • Aufreinigung

    Purified

    Reinheit

    Protein A affinity chromatography

    Immunogen

    Human protein was used as the immunogen for the recombinant b-Catenin antibody.

    Isotyp

    IgG kappa
  • Applikationshinweise

    Titration of the recombinant b-Catenin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

    1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. IHC (FFPE): 1-2 μg/mL,Prediluted IHC only format : incubate for 30 min at RT (1)

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Konservierungsmittel

    Azide free

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store the recombinant b-Catenin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
  • Target

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    Andere Bezeichnung

    Beta Catenin

    Hintergrund

    The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. [RefSeq]

    Pathways

    Peptide Hormone Metabolism
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