ABI1 Antikörper (C-Term)

Produktnummer ABIN5706835

Hersteller Produkt- Nr.: 600-401-gt5

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ABI1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für ABI1 Antikörper (C-Term) (ABIN5706835)

Target: ABI1 (Abl-Interactor 1 (ABI1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-ABI1 Antikörper

Bindungsspezifität: C-Term

Hersteller Produkt- Nr.: 600-401-gt5

Hersteller: Rockland

Verwendungszweck: Abi1 Antibody

Kreuzreaktivität (Details): Anti-Abi1 is directed against mouse Abi1.

Produktmerkmale: Synonyms: rabbit anti-Abi1 Antibody, Abi 1, Abi-1, Abl Interactor 1, Eps8 SH3 Domain-Binding Protein, Abl-Binding Protein, Abelson Interactor 1, E3B1, Spectrin SH3 Domain Binding Protein 1, Nap1-binding protein, SSH3BP1

Aufreinigung: This product is an affinity purified antibody produced by immunoaffinity chromatography using peptide coupled to agarose beads.

Sterilität: Sterile filtered

Immunogen:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to near c-terminal of the mouse Abi-1 protein.

Immunogen Type: Conjugated Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: This affinity purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 65 kDa in size corresponding to Abi1 by western blotting in the appropriate cell lysate or extract.

Western Blot Dilution: 1.0 μg/mL

ELISA Dilution: 5.0 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu ABI1

Target: ABI1 (Abl-Interactor 1 (ABI1))

Andere Bezeichnung: Abi1

Hintergrund: Background: Anti-Abi1 Antibody was designed, produced, and validated as part of the Joy Cappel Young Investigator Award (JCYIA). Abi1 gene has been suggested to have a role in inhibiting cell growth and encodes an adaptor protein in the Abelson-interactor family. The protein is involved in signal transduction, actin regulation and cytoskeletal remodeling. Studies suggest that Abi1 is a member of the WAVE complex and a dysfunctional complex may allow for the progression of prostate cancer. Anti-Abi1 is ideal for researchers interested in melanoma, colon and breast cancer and other cancer antibody research.

Gen-ID: 11308

NCBI Accession: NP_001070658

UniProt: Q8CBW3

Pathways: RTK Signalweg, Response to Water Deprivation, ER-Nucleus Signaling