ABI1 Antikörper

Produktnummer ABIN1449186

Der Maus Monoklonal anti-ABI1 Antikörper (Klon 1B9) (ABIN1449186) detektiert spezifisch ABI1 in WB, IP und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Hamster.

Kurzübersicht für ABI1 Antikörper (ABIN1449186)

Target: ABI1 (Abl-Interactor 1 (ABI1))

Reaktivität: Human, Maus, Hamster

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ABI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1B9

Produktdetails anti-ABI1 Antikörper

Spezifität: This antibody reacts with Abi-1.

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse, Hamster

Aufreinigung: Protein A agarose

Immunogen: Human recombinant Abi-1 expressed in E. coli

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store (in aliqouts) at -20 °C.

Details zu ABI1

Target: ABI1 (Abl-Interactor 1 (ABI1))

Andere Bezeichnung: ABI1 / SSH3BP1

Hintergrund: Abl interactor (Abi) proteins are c-Abl-binding proteins that bind to both the Src homology 3 (SH3) domain and the C-terminal proline-rich regions of Abl kinase through dual SH3-PXXP interactions. Two highly related genes, abi-1 and abi-2, were cloned. In addition to the interaction with Abl kinase, Abi proteins also interact with other signaling molecules. Recently, it has been reported that Abi-1 dramatically promoted c-Abl-mediated tyrosine (Tyr296) phosphorylation of Mena [mammalian homologue of Drosophila Enabled (Ena)] by interacting with both proteins.Synonyms: Abelson interactor 1, Abi-1, Abl interactor 1, Abl-binding protein 4, AblBP4, Eps8 SH3 domain-binding protein, Nap1-binding protein, Spectrin SH3 domain-binding protein 1, Spectrin binding protein, e3B1

Molekulargewicht: 65 kDa

Gen-ID: 10006

NCBI Accession: NP_001012768

UniProt: Q8IZP0

Pathways: RTK Signalweg, Response to Water Deprivation, ER-Nucleus Signaling