NME1 Antikörper

Produktnummer ABIN5704006

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch NME1 in WB, IHC, ELISA, IF und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für NME1 Antikörper (ABIN5704006)

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NME1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-NME1 Antikörper

Verwendungszweck: NME1 antibody

Immunogen: non-metastatic cells 1, protein (NM23A) expressed in

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab05762(NME1 antibody) at dilution of 1:1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu NME1

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Andere Bezeichnung: NME1

Hintergrund:

Synonyms: Nucleoside diphosphate kinase A (NDK A, NDP kinase A)|Granzyme A-activated DNase (GAAD)|Metastasis inhibition factor nm23|NM23-H1|Tumor metastatic process-associated protein|NME1|NDPKA|NM23

Background: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Molekulargewicht: 16-20 kDa

Gen-ID: 4830

UniProt: P15531

Pathways: Apoptose, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process