RFC5 Antikörper

Produktnummer ABIN5703736

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RFC5 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für RFC5 Antikörper (ABIN5703736)

Target: RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RFC5 Antikörper

Verwendungszweck: RFC5 antibody

Immunogen: replication factor C (activator 1) 5, 36.5kDa

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu RFC5

Target: RFC5 (Replication Factor C (Activator 1) 5, 36.5kDa (RFC5))

Andere Bezeichnung: RFC5

Hintergrund:

Synonyms: Replication factor C subunit 5|Activator 1 36 kDa subunit (A1 36 kDa subunit)|Activator 1 subunit 5|Replication factor C 36 kDa subunit (RF-C 36 kDa subunit, RFC36)|RFC5

Background: This gene encodes the smallest subunit of the replication factor C complex, which consists of five distinct subunits (140, 40, 38, 37, and 36 kDa) and is required for DNA replication. This subunit interacts with the C-terminal region of proliferating cell nuclear antigen and is required to open and load proliferating cell nuclear antigen onto DNA during S phase. It is a member of the AAA+ (ATPases associated with various cellular activities) ATPase family and forms a core complex with the 38 and 40 kDa subunits that possesses DNA-dependent ATPase activity. A related pseudogene has been identified on chromosome 9. Alternative splicing results in multiple transcript variants.

Gen-ID: 5985

UniProt: P40937

Pathways: Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA