BTK Antikörper
Kurzübersicht für BTK Antikörper (ABIN5702372)
Target
Alle BTK Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- BTK antibody
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Immunogen
- Bruton agammaglobulinemia tyrosine kinase
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
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Andere Bezeichnung
- BTK
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Hintergrund
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Synonyms: Tyrosine-protein kinase BTK|Agammaglobulinemia tyrosine kinase (ATK)|B-cell progenitor kinase (BPK)|Bruton tyrosine kinase|BTK|AGMX1|ATK|BPK
Background: The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Molekulargewicht
- 70-76 kDa
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Gen-ID
- 695
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UniProt
- Q06187
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Pathways
- Fc-epsilon Rezeptor Signalübertragung, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
Target
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